Acute Occlusion of the Infarct-Related Artery as a Predictor of Very Long-Term Mortality in Patients with Acute Myocardial Infarction

Table 2

Multivariant analysis.

Variable	HR	95% CI	value
Age	1,067	1,052–1,084	0
STEMI (no., %)	1,067	0,431–2,922	0,542
Atrial fibrillation (no., %)	1,832	0,527–1,537	0,176
Arterial hypertension (no., %)	1,832	0,623–1,421	0,68
Diabetes mellitus (no., %)	3,266	0,923–6,431	0,071
Smoking history (no., %)	0,433	0,230–1,021	0,805
Peripheral artery disease (no., %)	0,523	0,356–0,770	0,001
Carotid stenosis (no., %)	1,949	0,924–1,794	0,163
Previous myocardial infarction (no., %)	1,933	0,412–2,530	0,164
Previous coronary intervention (no., %)	1,997	0,876–2,233	0,158
Cardiogenic shock at admission (no., %)	1,738	0,764–2,325	0,187
Ventricular tachycardia before or during PCI (no., %)	0,253	0,133–0,481	0
Ventricular fibrillation before or during PCI (no., %)	0,003	0,012–2,124	0,96
Out-of-hospital arrest survivors (no., %)	0,282	0,123–4,344	0,596
SYNTAX (no., median (IQR))	0,305	0,120–2,311	0,581
PCI LMCA (no., %)	3,036	0,937–4,305	0,081
LMCA stenosis (no., %)	0,109	0,023–1,753	0,741
Hemoglobin (x10^12/L, median (IQR))	0,988	0,981–0,995	0,001
Leukocytes (x10^9/L, median (IQR))	0,698	0,252–3,591	0,967
Glucose (mmol/L, median (IQR))	1,051	1,030–1,073	0
Total cholesterol (mmol/L, median (IQR))	0,933	0,974–1,522	0,073
HDL (mmol/L, median (IQR));	0,152	0,098–1,101	0,696
LDL (mmol/L, median (IQR))	3,098	0,699–5,343	0,078
Triglycerides (mmol/L, median (IQR))	1,401	0,984–1,732	0,237
CK, admission value (U/L, median (IQR))	0,578	0,345–1,545	0,447
CK, maximal value (U/L, median (IQR))	2,982	0,923–5,830	0,084
LDH (U/L, median (IQR))	0,538	0,212–2,345	0,463
CRP (mg/L, median (IQR))	1,159	0,714–1,953	0,282
Left ventricular ejection fraction (%, median (IQR))	0,967	0,953–0,982	0
Severe aortic stenosis	0,476	0,229–0,989	0,027
Severe mitral regurgitation	0,6	0,405–0,899	0,011

Continuous variables are presented as median values with associated interquartile ranges. Categorical variables are expressed in absolute and relative frequencies. Cox regression (proportional hazards) regression was used to examine the independence of prognostic factors. HR, hazard ratio; 95% CI, confidence interval; values <0.05 were considered significant; IQR, interquartile range; STEMI, ST elevation myocardial infarction; PCI, percutaneous coronary intervention; SYNTAX, SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery; LMCA = left main coronary artery; LAD = left anterior descending artery; HDL = high-density lipoproteins; LDL = low-density lipoproteins; CK = creatine kinase; LDH = lactate dehydrogenase; CRP = C-reactive protein.