Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project
Table 2
Procedural and safety characteristics (N = 2534) by age groups divided into quartiles.
Procedural characteristics
TOTAL (n = 2534)
Age <53 (n = 584)
Age 53–61 (n = 630)
Age 61–67 (n = 594)
Age ≥67 (n = 726)
value
Procedure duration (min)
106.2 ± 46.5
110.0 ± 49.6
108.1 ± 45.8
104.0 ± 45.2
103.4 ± 45.3
0.064
Fluoroscopy time (min)
28.5 ± 27.4
28.5 ± 14.7
29.8 ± 48.0
27.8 ± 15.7
28.0 ± 15.5
1.000
Ablation time (min)
25.0 ± 17.5
26.0 ± 19.1
26.0 ± 17.2
23.9 ± 16.7
24.1 ± 17.0
0.0254,5
% Of isolated PVs (n treated veins/n target veins)
98.1% (9547/9729)
96.7% (2200/2269)
98.6% (2371/2404)
98.3% (2222/2261)
98.5% (2754/2795)
<0.0011,2,3
Left atrium dwell time (min)
57.0 ± 26.7
59.8 ± 28.5
58.1 ± 27.2
55.9 ± 26.0
54.8 ± 25.1
0.150
Patients with at least one complication
4.1% (104)
3.8% (22)
3.8% (24)
4.0% (24)
4.7% (34)
1.000
Permanent diaphragmatic paralysis
0.0% (1)
0.2% (1)
0.0% (0)
0.0% (0)
0.0% (0)
1.000
Transient diaphragmatic paralysis
1.8% (46)
1.5% (9)
2.2% (14)
1.9% (11)
1.7% (12)
1.000
Pericardial effusion
0.2% (6)
0.3% (2)
0.0% (0)
0.0% (0)
0.6% (4)
0.610
Femoral arterio-venous fistula
0.3% (7)
0.5% (3)
0.0% (0)
0.2% (1)
0.4% (3)
1.000
Cardiac tamponade
0.3% (7)
0.2% (1)
0.2% (1)
0.3% (2)
0.4% (3)
1.000
Pneumothorax/Hemothorax
0.0% (0)
0.0% (0)
0.0% (0)
0.0% (0)
0.0% (0)
–
Femoral pseudoaneurism
0.1% (3)
0.0% (0)
0.2% (1)
0.2% (1)
0.1% (1)
1.000
TIA
0.2% (3)
0.0% (0)
0.2% (1)
0.0% (0)
0.1% (2)
1.000
Hematoma
0.4% (9)
0.2% (1)
0.3% (2)
0.5% (3)
0.4% (3)
1.000
Other complication
0.9% (22)
0.9% (5)
0.8% (5)
1.0% (6)
1.0% (6)
1.000
1A significant difference between age<53 and age ≥53 and <61; 2a significant difference between age<53 and age ≥61 and <67; 3a significant difference between age<53 and age ≥67; 4a significant difference between age ≥53 and <61 and age ≥61 and <67; 5a significant difference between age ≥53 and <61 and age ≥67; 6a significant difference between age ≥61 and <67 and ag e≥67.
