Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project

Table 3

Procedural and safety characteristics (N = 2534) by three age groups.

Procedural characteristics	Total; (n = 2534)	“Very young”; Age ≤40; (n = 131)	“Intermediate age”; Age 41–74; (n = 2281)	“Very old”; Age ≥75; (n = 122)	value
Procedure duration (min)	106.2 ± 46.5	101.3 ± 43.3	107.0 ± 46.9	97.6 ± 41.3	0.124
Fluoroscopy duration (min)	28.5 ± 27.4	26.0 ± 13.3	28.8 ± 28.5	25.4 ± 12.1	0.344
Ablation time (min)	25.0 ± 17.5	23.5 ± 14.6	25.1 ± 17.8	23.9 ± 15.2	1.000
Left atrium dwell time (min)	57.0 ± 26.7	54.7 ± 23.3	57.5 ± 27.1	51.5 ± 20.4	0.622
Patients with at least one complication	4.1% (104)	2.3% (3)	4.3% (97)	3.3% (4)	1.000
Permanent diaphragmatic paralysis	0.0% (1)	0.0% (0)	0.0% (1)	0.0% (0)	–
Transient diaphragmatic paralysis	1.8% (46)	0.8% (1)	1.9% (43)	1.6% (2)	1.000
Pericardiac effusion	0.2% (6)	0.0% (0)	0.2% (5)	0.8% (1)	1.000
Femoral arterio-venous fistula	0.3% (7)	0.8% (1)	0.2% (5)	0.8% (1)	0.776
Cardiac tamponade	0.3% (7)	0.0% (0)	0.3% (7)	0.0% (0)	1.000
Pneumothorax/Hemothorax	0.0% (0)	0.0% (0)	0.0% (0)	0.0% (0)	–
Femoral pseudoaneurism	0.1% (3)	0.0% (0)	0.1% (3)	0.0% (0)	1.000
Stroke	0.0% (0)	0.0% (0)	0.0% (0)	0.0% (0)	–
TIA	0.1% (3)	0.0% (0)	0.1% (2)	0.0% (1)	1.000
Pulmonary vein stenosis	0.0% (0)	0.0% (0)	0.0% (0)	0.0% (0)	–
Hematoma	0.4% (9)	0.0% (0)	0.4% (9)	0.0% (0)	1.000
Other complication	0.9% (22)	0.8% (1)	1.0% (22)	0.0% (0)	1.000