Research Article

Associations between β-Blocker Therapy at Discharge and Long-Term Follow-Up Outcomes in Patients with Unstable Angina Pectoris

Table 1

Clinical characteristics of patients in the β-blocker and no β-blocker groups.

Before PS matchAfter PS match
β-Blocker (-) N = 1801β-Blocker (+) N = 3790 valueβ-Blocker (-) N = 1786β-Blocker (+) N = 1786 value

Age (years)65.0 ± 9.464.4 ± 9.50.03565.0 ± 9.465.0 ± 9.30.947
Male (%)1156 (64.2)2379 (62.8)0.3051142 (63.9)1145 (64.1)0.917
BMI (kg/m2)25.8 ± 3.426.1 ± 3.50.00425.8 ± 3.425.7 ± 3.40.298
SBP (mmHg)132 ± 17.2132.7 ± 17.30.144132.1 ± 17.2132.0 ± 16.70.790
DBP (mmHg)75.6 ± 11.476.8 ± 11.00.00175.8 ± 11.476.1 ± 10.90.387
Heart rate (bpm)66 (60,73)71 (64,78)<0.00166 (60,73)70 (64,78)<0.001

Medical history
Current smoker (%)569 (31.6)1186 (31.3)0.821562 (31.5)548 (30.7)0.613
Hypertension (%)1216 (67.5)2842 (75.0)<0.0011216 (68.1)1226 (68.6)0.719
DM (%)703 (39.0)1616 (42.6)<0.05700 (39.2)712 (39.9)0.681
Dyslipidemia (%)878 (48.8)1909 (50.4)0.258873 (48.9)862 (48.3)0.713
Stroke (%)286 (15.9)625 (16.5)0.563285 (16.0)297 (16.6)0.587
CHD (%)816 (45.3)1994 (52.6)<0.001815 (45.6)821 (46.0)0.840
OMI (%)104 (5.8)333 (8.8)<0.001104 (5.8)104 (5.8)1.000
CABG (%)27 (1.5)97 (2.6)0.01227 (1.5)27 (1.5)1.000
PCI (%)235 (13)696 (18.4)<0.001235 (13.2)229 (12.8)0.765

Medication used before admission
Antiplatelet agent (%)669 (37.1)1646 (43.4)<0.001669 (37.5)678 (38.0)0.756
ACEI/ARB (%)697 (38.7)1483 (39.1)0.759697 (39.0)720 (40.3)0.431
β-Blockers (%)154 (8.6)1378 (36.4)<0.001154 (8.6)605 (33.8)<0.001
Statins (%)595 (33.0)1345 (35.5)0.072594 (33.3)601 (33.7)0.804

Data are presented as mean ± SD, IQR, or n (%). BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; DM, diabetes mellitus; CHD, coronary heart disease; OMI, old myocardial infarction; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker.