Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients
Table 1
Baseline characteristics of studied patients with venoarterial extracorporeal membrane oxygenation (VA-EMCO).
All
Survivors (n = 35, 47.95%)
Nonsurvivors (n = 38, 52.05%)
z/χ/t
Gender
0.47
0.829
Male
53 (72.61)
25 (34.25)
28 (38.36)
Female
20 (27.4)
10 (13.7)
10 (13.7)
Age
57 (48–67)
56 (47,67)
60 (51.25, 66.25)
−0.354
0.724
APACHE II
27.63 (±6.65)
24.94 ± 1.226
30.11 ± 0.802
−3.523
0.001
BMI >35 kg/m2 (%)
29 (39.73)
13 (17.81)
16 (21.92)
0.187
0.665
Assist IABP (%)
27 (36.99)
15 (20.55)
12 (16.44)
0.994
0.319
Disease (%)
Acute myocardial infarction
24 (32.88)
14 (19.18)
10 (13.7)
11.923
0.012
Sudden cardiac death
2 (2.74)
2 (2.74)
0
14.362
0.003
Aortic dissection (type A)
16 (21.92)
4 (5.48)
12 (16.44)
14.904
0.002
Valvular heart disease
21 (28.77)
11 (15.07)
10 (13.7)
10.721
0.025
Infectious endocarditis
3(4.11)
3 (4.11)
0
15.112
0.001
Dilated cardiomyopathy
2 (2.74)
0
2 (2.74)
14.029
0.007
Exotic myocarditis
1 (1.37)
0
1 (1.37)
14.056
0.027
Other
4 (5.48)
1 (1.37)
3 (4.11)
12.672
0.021
Basic disease (%)
Type 2 diabetes
15 (20.55)
6 (8.22)
9 (12.33)
11.174
0.022
Hypertension
31 (42.47)
10 (13.7)
21 (28.77)
15.547
0.001
Hyperlipemia
11 (15.07)
6 (8.22)
5 (6.85)
11.202
0.022
AKI
62 (84.94)
26 (35.62)
36 (49.32)
5.954
0.015
Hemodialysis
50 (68.5)
18 (24.66)
32 (43.84)
9.073
0.03
Perfusion tube distal to the limb
67 (91.79)
31 (42.47)
36 (49.32)
0.918
0.338
Lower limb ischemia
9 (12.33)
2 (2.74)
7 (9.59)
2.722
0.099
Gastrointestinal bleeding
26 (35.62)
11 (15.07)
15 (20.55)
0.514
0.473
LVEF%
30.14
31.91
28.5
2.411
0.019
Gal-3-T0 (ng/ml)
14.61 (12.56–15.48)
14.16 (12.48, 15.44)
14.955 (12.6275, 15.725)
−1.336
0.181
Gal-3-T24
11.67 (9.395, 13.595)
10.1 (8.12, 11.75)
13.095 (11.32, 14.02)
−4.135
0.001
Gal-3-T72
9.28 (6.61, 11.875)
6.85 (5.34, 10.82)
11.105 (8.645, 12.87)
−4.395
0.001
BNP-T0 (pg/ml)
9970 (9494–10596)
9738 (9305, 10530)
10197.5 (9639.25, 10643.25)
−1.623
0.105
BNP-T24
6574 (6134.5, 7096)
6300 (5928, 6660)
6895 (6493.25, 7165.25)
−3.285
0.001
BNP-T72
6437 (3511.5, 7218)
3725 (3296, 6524)
6976.5 (6374, 7289.5)
−3.28
0.001
Plt
85 (57.50–117)
93 (72, 127)
66.5 (43.5, 108.25)
−2.612
0.009
Lac
2.1 (1.4, 3.4)
2.45 (1, 3.925)
−0.464
0.643
TECMO
5.8 (4.62–7.57)
5.96 (4.54, 7.73)
5.69 (4.745, 7.365)
−0.353
0.724
TICU
19.04 (13.92–26.15)
19.39 (15.31, 24.16)
18.78 (13.8225, 26.57)
−0.166
0.868
Normal distribution of measurement data is expressed as mean ± standard deviation (mean ± SD). Non-normal distribution is represented by the median, interquartile spacing (M (QL, QU)). Gal-3-T0 and BNP-T0 showed blood samples before ECMO, Gal-3-T24 and BNP-T24 at 24 h after ECMO, and Gal-3-T72 and BNP-T72 at 72 h after ECMO. TECMO refers to the duration of ECMO treatment patients, and TICU refers to the duration of the ICU stay.
