Efficacy of Boesenbergia rotunda Treatment against Thioacetamide-Induced Liver Cirrhosis in a Rat Model

Table 2

Liver function measured from the acute toxicity test of the BR extract on rats.

Dose	Total protein (g/L)	Albumin (g/L)	TB; (𝜇mol/L)	AP; (IU/L)	ALT; (IU/L)	AST; (IU/L)	GGT; (IU/L)
Vehicle (5 mL/kg)	71.37 ± 1.44	11.36 ± 0.53	1.91 ± 0.17	134.78 ± 9.57	53.05 ± 3.27	153.65 ± 9.35	4.91 ± 0.93
LD (2 g/kg)	71.47 ± 0.52	11.61 ± 0.34	2.18 ± 0.16	133.37 ± 8.63	51.90 ± 1.33	156.07 ± 3.56	5.00 ± 1.23
HD (5 g/kg)	71.81 ± 1.03	11.72 ± 0.16	1.88 ± 0.21	135.13 ± 6.52	52.27 ± 3.25	155.00 ± 5.35	5.32 ± 1.07

TB: total bilirubin; AP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase. The values were expressed as mean ± S.E.M. There were no significant differences between the three groups. Significant value was at 𝑃<0.05.