Polyphenol-Rich Fraction of Brown Alga Ecklonia cava Collected from Gijang, Korea, Reduces Obesity and Glucose Levels in High-Fat Diet-Induced Obese Mice

Figure 1

Effect of CA or G-CA extracts on body weight and food intake. Three weeks after beginning a high-fat diet, C57BL6 mice were orally administered CA or G-CA extract (200 mg/kg body weight) or PBS daily for 8 weeks. (a) Body weights were monitored weekly. (b) Food intake was measured weekly. Values are the average weight of food consumed/mouse/day. NC: untreated, normal chow diet, 𝑛=7; PBS: PBS-treated, high-fat diet (HFD), 𝑛=6; CA: CA-treated, HFD, 𝑛=5; and G-CA: G-CA-treated, HFD, 𝑛=5. Values are mean ± SE. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus NC group; ^#𝑃<0.05, ^##𝑃<0.01 versus PBS-HFD group; ^$𝑃<0.05 versus CA-HFD. PO is an abbreviation of per oral.

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