Evidence-Based Complementary and Alternative Medicine

Research Article

Antimicrobial Activity of Essential Oils against Streptococcus mutans and their Antiproliferative Effects

Table 1

Medicinal and aromatic plants from the germplasm bank of the CPMA/CPQBA/UNICAMP selected for this study with their yield, MIC and MBC values, and MBC : MIC ratio.


Medicinal species	Family	Popular name	Source	CPMA number	Voucher number¹	Yield (%)	MIC (μg/mL)	MBC (μg/mL)	MBC : MIC ratio²	Popular use

Aloysia gratissima (Gillies & Hook)	Verbenaceae	Brazilian lavender	Leaf	714	UEC 121.393	1.1	125–250	250–500	2 : 1	Digestive; antispasmodic
Aloysia triphylla (L’Hér.) Britton	Verbenaceae	Aloisia	Leaf	274/700	UEC 121.412	0.3	125–250	125–250	1 : 1	Sedative; antispasmodic
Alpinia speciosa (Pers.) Burtt & Smith	Zingiberaceae	Colony	Root	447	UEC 145.185	0.2	125–250	250–500	2 : 1	Antimicrobial
Baccharis dracunculifolia DC	Asteraceae	Broom weed	Leaf	1841	—	0.8	62.5–125	250–500	4 : 1	Tonic; eupeptic, antipyretic
Cinnamomum zeylanicum Blume	Lauraceae	Cinnamon	Leaf	455	IAC 19624	0.2	250–500	500–1000	2 : 1	Carminative; antispasmodic
Coriandrum sativum L.	Apiaceae	Coriander	Leaf	664	—	0.3	31.2–62.5	62.5–125	2 : 1	Antimicrobial; antifungal
Cymbopogon citratus (DC) Stapf.	Poaceae	Lemon grass	Leaf	503	UEC 85.210	1.1	125–250	250–500	2 : 1	Sedative; analgesic; anticough
Cymbopogon martini (Roxb.) J. F. Watson	Poaceae	Palmarosa	Leaf	354	UEC 127.115	0.6	125–250	250–500	2 : 1	Antiseptic; antifungal
Cymbopogon winterianus Jowitt	Poaceae	Lemon verbena	Leaf	712	UEC 121.414	1.5	125–250	250–500	2 : 1	Repellent, insecticide
Cyperus articulatus Vahl	Cyperaceae	Priprioca	Bulbs	222	UEC 121.396	0.5	125–250	250–500	2 : 1	Anti-inflammatory
Elyonurus muticus Spreng	Poaceae	Agripalma	Leaf	1701	UEC 20.580	0.6	125–250	125–250	1 : 1	Antibacterial
Eugenia florida DC.	Myrtaceae	Guamirim-cereja	Leaf	1685	IAC 49207	0.3	125–250	500–1000	4 : 1	Anti-inflammatory
Eugenia uniflora L.	Myrtaceae	Pitanga	Leaf	1816	—	0.7	125–250	250–500	2 : 1	Antihypertensive; diuretic
Lippia alba (Mill.) N.E. Brown	Verbenaceae	False lemon balm	Leaf	467/509	UEC 121.413	0.3	125–250	250–500	2 : 1	Treatment of migraines
Lippia sidoides Cham.	Verbenaceae	Rosemary	Leaf	398/399	—	4.7	62.5–125	125–250	2 : 1	Bactericide; fungicide
Mentha piperita L.	Lamiaceae	Mint	Leaf	560	UEC 127.110	2.2	250–500	250–500	1 : 1	Antifungal; antibacterial
Mikania glomerata Spreng.	Asteraceae	Guaco	Leaf	766	UEC 102.047	0.4	62.5–125	125–250	2 : 1	Anti-inflammatory; bronchodilator
Siparuna guianenses Aubl.	Monimiaceae	Wild lemon	Leaf	2025	—	0.3	62.5–125	125–250	2 : 1	Tranquilizer; diuretic
Syzygium aromaticum (L.) Merr. & L. M. Perry	Myrtaceae	Cloves	Leaf	455	IAC 19624	0.5	62.5–125	250–500	4 : 1	Seasoning; antibacterial
Ziziphus joazeiro Mart.	Rhamnaceae	Joazeiro fruit	Leaf	2119	—	0.5	250–500	500–1000	2 : 1	Astringent; anti-inflammatory

¹A voucher herbarium specimen is a pressed plant sample deposited for future reference. Vouchers deposited at UEC herbarium (http://www.ib.unicamp.br/herbario/) at Biology Institute (IB) of UNICAMP, SP, Brazil. (—) Species with no voucher number registered. ²The EOs were considered bactericidal when the MBC : MIC ratio was between 1 : 1 to 2 : 1, and bacteriostatic if this ratio was higher than 2 : 1.