Mechanisms of Gastroprotective Effects of Ethanolic Leaf Extract of Jasminum sambac against HCl/Ethanol-Induced Gastric Mucosal Injury in Rats
Table 1
(a) Effect s of J. sambac extract on kidney biochemical parameters in male rats. (b) Effect s of J. sambac extract on kidney biochemical parameters in female rats. (c) Effect s of J. sambac extract on liver biochemical parameters in male rats. (d) Effect s of J. sambac extract on liver biochemical parameters in female rats.
(a)
Dose
Sodium (mmol/L)
Pottasium (mmol/L)
Chloride (mmol/L)
CO2 (mmol/L)
Anion gap (mmol/L)
Urea (mmol/L)
Creatinine (μmol/L)
Vehicle (CMC)
141.33 ± 0.58
4.98 ± 0.04
103.88 ± 0.82
24.12 ± 0.54
18.75 ± 0.46
5.45 ± 0.45
34.83 ± 2.17
LD (2 g/kg)
142.05 ± 0.55
5.02 ± 0.09
105.29 ± 1.02
22.67 ± 0.81
18.55 ± 0.62
6.06 ± 0.83
33.87 ± 2.29
HD (5 g/kg)
143.14 ± 0.68
4.91 ± 0.06
104.35 ± 0.54
23.90 ± 0.64
19.15 ± 0.45
5.63 ± 0.37
35.05 ± 2.26
(b)
Dose
Sodium (mmol/L)
Pottasium (mmol/L)
Chloride (mmol/L)
CO2 (mmol/L)
Anion gap (mmol/L)
Urea (mmol/L)
Creatinine (μmol/L)
Vehicle (CMC)
141.87 ± 0.42
4.83 ± 0.14
105.78 ± 0.67
23.33 ± 0.41
18.00 ± 0.25
7.95 ± 0.33
41.76 ± 2.75
LD (2 g/kg)
142.07 ± 0.56
4.55 ± 0.16
105.85 ± 0.65
22.65 ± 0.42
17.49 ± 0.46
7.97 ± 0.49
42.00 ± 2.36
HD (5 g/kg)
142.15 ± 0.47
4.63 ± 0.18
107.03 ± 0.53
21.96 ± 0.75
17.67 ± 0.48
8.31 ± 0.68
43.13 ± 2.24
Values expressed as mean ± S.E.M. There are no significant differences between groups. Significant value at .
(c)
Dose
Total protein (g/L)
Albumin (g/L)
Globulin (g/L)
TB (μmol/L)
CB (μmol/L)
AP (IU/L)
ALT (IU/L)
AST (IU/L)
GGT (IU/L)
Vehicle (CMC)
60.45 ± 1.25
9.62 ± 0.49
52.02 ± 1.40
2.17 ± 0.17
1.00 ± 0.00
153.00 ± 6.35
50.08 ± 1.62
172.95 ± 6.13
3.26 ± 0.25
LD (2 g/kg)
58.86 ± 0.86
8.81 ± 0.38
50.71 ± 1.21
2.13± 0.16
1.00 ± 0.00
154.17 ± 8.10
48.33 ± 0.58
174.23 ± 5.14
3.65 ± 0.42
HD (5 g/kg)
60.15 ± 1.05
9.17 ± 0.46
50.33 ± 1.24
2.02 ± 0.13
1.00 ± 0.00
155.00 ± 7.04
47.87 ± 1.55
175.15 ± 7.02
3.37 ± 0.18
(d)
Dose
Total protein (g/L)
Albumin (g/L)
Globulin (g/L)
TB (μmol/L)
CB (μmol/L)
AP (IU/L)
ALT (IU/L)
AST (IU/L)
GGT (IU/L)
Vehicle (CMC)
64.33 ± 1.26
11.19 ± 0.17
53.17 ± 1.28
2.00 ± 0.00
1.00 ± 0.00
108.83 ± 4.13
43.17 ± 2.91
171.83 ± 6.38
3.67 ± 0.33
LD (2 g/kg)
63.75 ± 1.19
11.05 ± 0.45
52.33 ± 1.26
2.00 ± 0.00
1.00 ± 0.00
98.83 ± 5.25
42.96 ± 2.70
172.17 ± 6.35
3.50 ± 0.51
HD (5 g/kg)
65.02 ± 2.65
11.30 ± 0.43
53.02 ± 1.25
2.00 ± 0.00
1.00 ± 0.00
102.67 ± 5.17
44.02 ± 1.85
174.28 ± 5.26
3.22 ± 0.44
Values expressed as mean ± S.E.M. There are no significant differences between groups. Significant value at . TB: total bilirubin; CB: conjugated bilirubin; AP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: G-glutamyl transferase.