Evidence-Based Complementary and Alternative Medicine

Research Article

Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet

Table 5

Plasma lipid profile and the ratio of TC to HDL-C at week 0 (baseline), week 4, and week 8.


	NC	PC	HS	HPO	HKO	HF	HD

TC (mmol/L)
Week 0	1.79 ± 0.06^a,1	1.54 ± 0.06^a,1	1.58 ± 0.09^a,1	1.16 ± 0.03^a,1	0.84 ± 0.03^a,1	1.23 ± 0.01^a,1	0.89 ± 0.02^a,1
Week 4	2.21 ± 0.04^a,2	19.58 ± 0.81^d,2	9.54 ± 0.38^b,2	20.4 ± 0.37^d,2	21.36 ± 0.59^d,2	12.33 ± 0.47^c,2	4.21 ± 0.19^a,2
Week 8	1.94 ± 0.02^a,1	34.42 ± 0.84^c,3	3.74 ± 0.11^a,3	24.83 ± 0.88^b,3	24.26 ± 0.61^b,3	33.61 ± 0.99^c,3	1.29 ± 0.02^a,1

LDL-C (mmol/L)
Week 0	0.66 ± 0.03^a,1	0.62 ± 0.03^a,1	0.65 ± 0.02^a,1	0.53 ± 0.21^a,1	0.28 ± 0.18^a,1	0.58 ± 0.04^a,1	0.29 ± 0.02^a,1
Week 4	1.02 ± 0.05^a,2	11.94 ± 0.06^c,2	5.97 ± 0.12^b,2	13.17 ± 0.89^c,2	6.36 ± 0.42^c,2	14.91 ± 0.61^b,2	3.00 ± 0.22^ab,2
Week 8	0.66 ± 0.05^a,1	14.84 ± 1.26^c,2	3.99 ± 0.31^a,3	14.83 ± 1.42^b,2	17.37 ± 1.14^c,3	17.97 ± 1.18^c,2	10.90 ± 0.59^b,3

HDL-C (mmol/L)
Week 0	0.59 ± 0.04^c,1	0.36 ± 0.02^ab,1	0.49 ± 0.03^bc,1	0.37 ± 0.03^ab,1	0.35 ± 0.02^ab,1	0.55 ± 0.04^c,1	0.30 ± 0.03^a,1
Week 4	0.6 ± 0.04^a,1	2.81 ± 0.11^c,2	2.46 ± 0.03^c,2	4.08 ± 0.38^d,2	1.59 ± 0.07^c,2	2.62 ± 0.22^b,2	0.68 ± 0.16^a,1
Week 8	0.57 ± 0.04^a,1	3.59 ± 0.19^d,3	1.29 ± 0.13^a,3	2.79 ± 0.21^c,3	3.31 ± 0.11^d,3	4.12 ± 0.24^e,3	1.91 ± 0.11^b,2

TG (mmol/L)
Week 0	0.64 ± 0.01^a,1	0.65 ± 0.06^a,1	0.56 ± 0.02^a,1	0.69 ± 0.05^a,1	0.65 ± 0.03^a,1	0.69 ± 0.05^a,1	0.75 ± 0.11^a,1
Week 4	0.54 ± 0.01^c,2	0.48 ± 0.03^ab,1	0.59 ± 0.12^a,1	0.7 ± 0.05^a,1	0.77 ± 0.07^a,1	0.43 ± 0.03^b,1	1.07 ± 0.08^d,1
Week 8	0.51 ± 0.04^a,1	1.28 ± 0.09^c,2	0.56 ± 0.04^a,1	1.28 ± 0.05^c,2	1.58 ± 0.07^c,1	1.18 ± 0.12^b,2	1.03 ± 0.02^c,1

TC : HDL ratio
Week 0	2.99 ± 0.01^b,1	4.29 ± 0.11^d,1	3.22 ± 0.08^b,2	3.13 ± 0.05^b,1	3.50 ± 0.09^c,2	1.53 ± 0.06^a,1	2.91 ± 0.14^b,2
Week 4	3.68 ± 0.01^a,2	6.98 ± 0.19^a,2	3.88 ± 0.07^a,3	5.01 ± 0.11^b,2	7.74 ± 0.50^d,3	8.14 ± 0.70^e,3	6.22 ± 0.15^c,3
Week 8	3.39 ± 0.08^b,3	9.57 ± 0.11^b,3	1.36 ± 0.14^a,1	8.88 ± 0.10^d,3	10.15 ± 0.42^e,1	5.89 ± 0.09^c,2	0.67 ± 0.02^a,1

Value represents the mean ± SEM (). Values for a given parameter in a row that do not share the same superscript letter are significantly different at . Values for a given parameter in each column that do not share the same superscript number are significantly different at . NC: normal control, PC: positive control, HS, HPO, HKO, HF, and HD: hypercholesterolemic diet treated with simvastatin, 20 g kg⁻¹ of pulp oil, 20 g kg⁻¹ kernel oil, 50 g kg⁻¹ fullfat pulp, or 50 g kg⁻¹ defatted pulp, respectively.