Caffeic Acid Phenylethyl Amide Protects against the Metabolic Consequences in Diabetes Mellitus Induced by Diet and Streptozocin

Figure 2

Fat metabolism of mice. (a) Body weight before (0W) and after two (2W) and four (4W) weeks of diet exposure. (b and c) Fat mass and fat to body weight ratio after 4 weeks of diet exposure. (d and e) Plasma levels of retinol binding protein 4 (RBP4) and adiponectin after 4 weeks of diet exposure. 𝑛= 6–8 per group; means ± SEM; Con: control mice; HF: mice fed with high fat and diet; HFCA: HF mice treated with CAPA; HFMET: HF mice treated with metformin; *: 𝑃<0.05 versus Con; #: 𝑃<0.05 versus HF.

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