Caffeic Acid Phenylethyl Amide Protects against the Metabolic Consequences in Diabetes Mellitus Induced by Diet and Streptozocin
Table 1
Food and water intake of mice after 4 weeks of diet exposure.
Basal
After 4 weeks of diet exposure
Con
HF
HC
HM
Body weight (g)
25.6 0.4
35.5 0.8
40.2 1.0*
37.2 0.6#
35.0 1.1#
Night food intake (g)
4.5 0.5
6.0 0.5
4.3 0.8*
2.4 0.3#
2.4 0.4#
Night water intake (mL)
10.5 0.6
12.2 0.2
6.4 0.6*
5.9 0.3
6.4 0.5
Night calorie intake
Food (kcal)
14.4 1.3
18.1 1.4
19.8 2.2
12.5 0.9#
11.1 1.7#
Water (kcal)
—
—
5.5 0.3
4.1 0.5
5.1 0.4
Total (kcal)
14.4 1.3
18.1 1.4
25.3 2.2*
16.6 0.8#
15.9 4.4#
Con: control mice; HF: mice fed with high fat and diet; HC: HF mice treated with CAPA; HM: HF mice treated with metformin; *: P < 0.05 versus Con; #: P < 0.05 versus HF; n= 6–8 per group.