Tongguan Capsule Protects against Myocardial Ischemia and Reperfusion Injury in Mice

Figure 1

Experimental protocols. Four groups (SHAM, I/R, VER, and TGC groups) of mice were studied for infarct size analysis. Days 1–3: mice were subjected to either saline (SHAM and I/R groups) or TGC via direct gastric gavage daily. Day 4: mice in SHAM, I/R, TGC, and VER groups (verapamil 20 mg/kg i.p pretreatment) were subjected to a 30 min LAD occlusion. Day 5: after 24 h of reperfusion following LAD occlusion, all animals were sacrificed for subsequent measurement of infarct size.