Tongguan Capsule Protects against Myocardial Ischemia and Reperfusion Injury in Mice

Table 2

Size of left ventricle, risk region and infarction in study.

	SHAM	I/R	VER	TGC
LV Wt, mg	99.0±4.6	100.3±4.9	90.7±2.6	95.4±2.9
Risk region Wt, mg	41.4±4.6	44.8±3.2	58.5±6.4	59.2±3.5
Infarct Wt, mg	0.9±0.5	13.6±1.1	9.8±1.3	11.5±1.0
Risk region, % of LV	51.9±6.4	51.6±3.6	65.5±5.5	62.1±3.2
Infarct, % of risk region	2.7±1.2	30.2±2.7^#	17.1±2.4^∗∗	19.3±2.0^∗∗
Infarct, % of LV	1.1±0.5	11.5±1.1^#	7.8±1.0^∗	8.0±0.8^∗

Data are mean ± SEM. LV Wt: left ventricular weight; RR: region at risk. There were no significant differences in the age, sex, and LV weight of the mice among the four groups. Also, there were no significant differences in the region at risk among the four groups. ^#𝑃<0.001 I/R group compared with SHAM, *𝑃<0.05, *𝑃<0.01 IS (percentage of LV and RR) in TGC and VER groups versus I/R group, respectively.