Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana
Figure 3
The effect of glutathione (GSH) on the number of parasites preincubated with 0.5 μg/mL mexicanin I (Mxc), psilostachyin (Psi) or psilostachyin C (Psi C) or with 2.5 μg/mL of dehydroleucodine (DhL), for 30 min (a) or preincubated 1 h with the lactones and followed by withdrawal of the compounds before adding the reducing agent (b). Bars represent the means of parasite concentration ± SD from three independent experiments. (**) and (*) indicate significant differences with the control ( and resp.).
