Beta-Glucan-Rich Extract from Pleurotus sajor-caju (Fr.) Singer Prevents Obesity and Oxidative Stress in C57BL/6J Mice Fed on a High-Fat Diet

Table 3

Effects of GE and metformin on lipid profile and AI in C57BL/6J mice fed on a high-fat diet or normal diet.

Groups	Serum concentration (mmol/L)
	TG	TC	HDL-c	LDL-c	AI
ND	0.60±0.02^ab	2.03±0.5^a	1.87±0.05^a	0.14±0.0^ab	0.07
ND240	0.70±0.02^b	1.80±0.4^a	1.79±0.01^a	0.01±0.0^a	0.01
HFD	0.8±0.2^bc	2.80±0.3^b	2.52±0.3^b	0.38±0.1^c	0.11
HFD60	0.70±0.1^b	2.60±0.2^b	2.35±0.2^b	0.15±0.0^ab	0.11
HFD120	0.60±0.1^ab	2.50±0.2^ab	2.41±0.3^b	0.07±0.0^a	0.07
HFD240	0.60±0.4^ab	2.10±0.1^a	2.35±0.2^b	0.02±0.0^a	0.02
HFDMET	0.50±0.0^a	2.60±0.3^b	2.55±0.3^b	0.18±0.0^ab	0.02

Values expressed are means ± S.D of (𝑛=6 per group) measurements. For same assay with various treatment groups, superscripts in the different bar with different alphabets (a–c) were significantly different (𝑃<0.05). Superscripts with same alphabets were not significantly different between the treated groups (𝑃>0.05). TG is triglycerides; TC is total cholesterol; HDL-c is high-density lipoprotein cholesterol; LDL-c is low-density lipoprotein cholesterol; AI is atherogenic index.