Beta-Glucan-Rich Extract from Pleurotus sajor-caju (Fr.) Singer Prevents Obesity and Oxidative Stress in C57BL/6J Mice Fed on a High-Fat Diet

Table 4

Effects of GE and metformin on liver enzymes in C57BL/6J mice fed on a high-fat diet or normal diet.

Groups	Liver enzymes (mmol/L)
	Alanine transaminase; (ALT)	Aspartate transaminase; (AST)	Alkaline phosphate (ALP)	G-glutamyl transferase (GGT)
ND	45±1.2^c	182±11.2^b	39±1.2^a	<3
ND240	29±1.1^a	148±10.2^a	30±1.1^a	<3
HFD	48±1.4^c	210±8.2^c	54±0.9^c	<3
HFD60	46±2.3^c	194±12.1^b	44±1.4^b	<3
HFD120	32±2.4^b	181±10.1^b	38±1.3^a	<3
HFD240	27±1.4^a	176±9.7^ab	35±1.3^a	<3
HFDMET	39±1.33^b	189±9.5^b	39±1.5^a	<3

GE concentrations were 60, 120, and 240 mg/kg/day. Metformin (MET) is used as positive control. Values expressed are means ± S.D of triplicate measurements. For same enzyme level with various treatment groups, superscripts in the different bar with different alphabets (a–c) were significantly different (𝑃<0.05). Superscripts with same alphabets were not significantly different between the treated groups (𝑃>0.05).