Research Article

Novel Antidepressant-Like Activity of Propolis Extract Mediated by Enhanced Glucocorticoid Receptor Function in the Hippocampus

Figure 3

Effects of propolis extract on locomotor activity in the open-field test. After the TST, the spontaneous motor activity of mice was measured by the open-field test. The number of times a gridline was crossed with all four paws was scored during the 10 min test period. The error bars represent the means ± SEM ( per group). Data were analyzed using one-way ANOVA followed by Tukey’s post hoc tests. The columns and error bars represent means ± SEM ( per group). Data were analyzed using a one-way ANOVA followed by Tukey’s post hoc test. P50: propolis extract (50 mg/kg); P100: propolis extract (100 mg/kg); P200: propolis extract (200 mg/kg).
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