Novel Antidepressant-Like Activity of Propolis Extract Mediated by Enhanced Glucocorticoid Receptor Function in the Hippocampus

Figure 5

Effect of propolis extract treatment on serum corticosterone levels in mice exposed to the FST. Trunk blood was collected 30 min after the FST. The no FST (naive) group served as the control group. The columns and error bars represent means ± SEM (𝑛=10 per group). Data were analyzed using a one-way ANOVA followed by Tukey’s post hoc test. P50: propolis extract (50 mg/kg); P100: propolis extract (100 mg/kg); P200: propolis extract (200 mg/kg). ^##𝑃<0.01 versus naive; ^∗∗𝑃<0.01 versus vehicle.