Research Article
Bioinformatics Analysis for the Antirheumatic Effects of Huang-Lian-Jie-Du-Tang from a Network Perspective
Table 1
KEGG pathways significantly enriched with targets of HLJDT’s components.
| Pathway class | Pathway name | Total genes on pathway | HLJDT’s targets on pathway |
| Cell communication | Focal adhesion | 200 | 14 | Cell growth and death | p53 signaling pathway | 69 | 13 | Apoptosis | 86 | 14 | Development | Osteoclast differentiation | 128 | 13 | Immune system | Toll-like receptor signaling pathway | 102 | 13 | T-cell receptor signaling pathway | 108 | 13 | NOD-like receptor signaling pathway | 59 | 9 | B-cell receptor signaling pathway | 75 | 9 | Chemokine signaling pathway | 189 | 11 | Nervous system | Neurotrophin signaling pathway | 127 | 12 | Signal transduction | VEGF signaling pathway | 76 | 10 | MAPK signaling pathway | 272 | 15 | Signaling molecules and interaction | Cytokine-cytokine receptor interaction | 275 | 15 |
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