Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas

Figure 6

Scheme of the andrographolide regulatory pathway. The effects of andrographolide inhibition of lung tumors are hypothesized through a cell-cycle signaling pathway. The diagram shows that andrographolide may inhibit VEGF-A, KDR, Nrp1, ERK2, Cyclin A, and Cyclin B expression.