Paeonol, a Major Compound of Moutan Cortex, Attenuates Cisplatin-Induced Nephrotoxicity in Mice
Figure 3
Survival in cisplatin-treated mice and paeonol-pretreated mice. (a) All mice received a single dose of cisplatin intraperitoneally (30 mg/kg body wt) and were followed up to 78 h. Compared with a 60 median survival time in cisplatin-treated group, paeonol-pretreated group had a 78 median survival time. Data were analyzed by a Kaplan-Meier test ( versus Cis; ). (b) Mice received cisplatin intraperitoneally (20 or 10 mg/kg body wt) and were followed up to 72 h. Data were analyzed by a Kaplan-Meier test ( versus Cis; ).
