Ampelopsis Radix Protects Dopaminergic Neurons against 1-Methyl-4-phenylpyridinium/1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Toxicity in Parkinson’s Disease Models In Vitro and In Vivo
Figure 4
Inhibitory effects of AJW on behavioral impairment by MPTP in mice. Saline or AJW at 10 or 100 mg/kg/day was administered orally for 7 days, and MPTP 20 mg/kg was injected intraperitoneally four times at 2 h intervals on the last day of AJW treatment. Seven days after the last MPTP injection, we conducted the pole test. The time taken for the mice to turn completely downward ((a); T-turn) and the time taken to reach the floor ((b); T-LA) were recorded. Values are indicated as the mean ± SEM. ** compared with the control group, ### compared with the MPTP-only treated group.
