Research Article

Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine

Figure 7

Cryptolepine (CAS) inhibited p38 phosphorylation in LPS-activated microglia. Cells were stimulated with LPS (100 ng/mL) in the presence or absence of CAS (2.5 and 5 μM) for 30 min. At the end of incubation period, phospho-p38 protein expression was determined using western blot with specific anti-phospho-p38 antibody. All values are expressed as mean ± SEM for 3 independent experiments. Data were analysed using one-way ANOVA for multiple comparison with post hoc Student Newman-Keuls test. * in comparison with LPS control.
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