Research Article

Wenxin-Keli Regulates the Calcium/Calmodulin-Dependent Protein Kinase II Signal Transduction Pathway and Inhibits Cardiac Arrhythmia in Rats with Myocardial Infarction

Figure 3

The expression levels of CaMKII and related proteins in the interventricular septum and left ventricle after the 4-week treatment period. (a) The expression levels of CaMKII, p-CaMKII (Thr-286), PLB, RyR2, p-PLB (Thr-17), and FKBP12.6 in the interventricular septum of the four groups. (b) The expression of CaMKII, p-CaMKII (Thr-286), PLB, RyR2, p-PLB (Thr-17), and FKBP12.6 in the left ventricle of the four groups. (c) The expression level of CaMKII of the four groups in the interventricular septum and the left ventricle. (d) The expression level of Thr-286-phosphorylated CaMKII of the four groups in the interventricular septum and the left ventricle. (e) The expression level of PLB of the four groups in the interventricular septum and the left ventricle. (f) The expression level of Thr-17-phosphorylated PLB of the four groups in the interventricular septum and the left ventricle. (g) The expression level of RyR2 of the four groups in the interventricular septum and the left ventricle. (h) The expression of FKBP12.6 of the four groups in the interventricular septum and the left ventricle. (* versus the MI group, versus the sham group, and # the amiodarone group versus the WXKL group).
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