Research Article

Wenxin-Keli Regulates the Calcium/Calmodulin-Dependent Protein Kinase II Signal Transduction Pathway and Inhibits Cardiac Arrhythmia in Rats with Myocardial Infarction

Figure 5

Effects of WXKL on the incidences of EADs and DADs in vitro at 4 weeks after treatment. (a) The incidences of EADs and DADs were recorded among the sham group, the MI group, the WXKL group, and the amiodarone group (  cells per group). (b) The incidence of EADs was significantly increased in the MI group compared with the sham group, the WXKL group, and the amiodarone group (29.4% versus 6.3%, 12.5% and 17.6%, respectively; using Fisher’s 2-sided exact test). (c) The incidence of DADs was significantly increased in the MI group compared with the sham group, the WXKL group, and the amiodarone group (79.1% versus 15.5%, 30.5% and 39.7%, respectively; using Fisher’s 2-sided exact test). (* versus the MI group, versus the sham group).
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