Research Article

Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea

Figure 3

Effects of R. rosea constituents on iNOS protein expression in LPS-treated microglial cell. BV2 microglial cells were treated with the Rhodiola rosea constituents (1, 10, 50 μg/mL) 30 min prior to activation by 100 ng/mL LPS. The protein was collected after 18 h. The iNOS protein levels were measured using immunoblot analysis. R. rosea active components suppressed the LPS-induced expression of iNOS protein in activated microglia. Results are representative of three independent experiments. Data were analyzed by one-way ANOVA for multiple comparison and Student-Newman-Keuls test as post hoc test. # as compared with the vehicle group; * as compared with the LPS treated group.
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