Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug
Figure 4
Pathways altered by EEDS treatment in A549 cells. Statistically significant pathways in (a) the Down-pattern, (b) the Up-pattern, and (c) the combined Down- and Up-patterns were analyzed by implementing the SPIA program. The horizontal or vertical axis represents the overrepresentation of a pathway () or the perturbation of a pathway (), respectively. Red or blue dotted lines represent the Bonferroni- or FDR- corrected thresholds of significance (1%), respectively, for each axis value. Red and blue circles are significant pathways after Bonferroni and FDR correction (1%) of the global values (), respectively. A list of pathways consisting of red circles (Bonferroni corrected ) is shown below.
