Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug
Table 2
Top 20 list of genes mostly down-regulated or up-regulated by EEDS.
Down-pattern
Up-pattern
Symbol
EEDS (μg/mL)
Symbol
EEDS (μg/mL)
1.25
5
20
1.25
5
20
CSRP2BP
HBEGF
0.86
1.58
4.44
SCARA5
C7orf53
2.86
2.73
4.46
HOXB13
SERPINE1
1.54
3.50
4.59
FOXS1
CD274
2.59
3.23
4.60
SNORA12
NOG
1.16
3.91
4.67
RIMBP3
PER1
2.22
1.52
4.68
ST6GAL1
ARC
0.78
1.69
4.79
DACT2
GADD45B
1.23
1.95
4.82
TMEM37
LTB
1.37
4.06
4.85
EEF2K
FOS
1.25
0.52
4.87
GPRIN2
DDIT3
1.66
2.78
4.90
SALL2
C3orf52
1.04
2.26
4.96
CBR3
MAFF
1.62
2.70
5.07
FANCF
IL8
2.94
4.52
5.55
CCR7
PPP1R15A
1.42
2.61
5.59
C5orf58
LOC387763
3.52
4.33
5.67
VAV3
ATF3
1.02
2.49
5.69
C14orf93
EGR2
0.11
0.72
6.46
NTHL1
FOSB
1.36
3.75
7.85
VASH1
EGR1
1.44
4.10
10.02
Fold induction represents expression ratio of gene compared with that of control.