Inhibition of NADPH Oxidase Mediates Protective Effect of Cardiotonic Pills against Rat Heart Ischemia/Reperfusion Injury
Figure 1
CP pretreatment reduces I/R-induced infarct size. (a) Representative images of myocardial tissue slices stained with TTC in Sham group (a1), I/R group (a2), CP group (a3), CP group (a4), and CP group (a5). White territory represents infarct area. (b) Quantitative results of infarct size in each group. Sham: Sham group; I/R: ischemia/Reperfusion group; CP : CP pretreatment at 0.1 g/kg/day for 6 days plus I/R operation; CP 0.4 + I/R: CP pretreatment at 0.4 g/kg/day for 6 days plus I/R operation; CP 0.8 + I/R: CP pretreatment at 0.8 g/kg/day for 6 days plus I/R operation. The treatment of animals in each group is detailed in Section 2. Results are presented as mean ± SEM (). versus Sham group, versus I/R group.
