Research Article
Differences of Excess and Deficiency Zheng in Patients with Chronic Hepatitis B by Urinary Metabonomics
Table 6
Disturbed pathways of EZ and DZ compared to WZ group.
| Pathway | -val EZ versus WZ | -val DZ versus WZ | Class | Annotation |
| ABC transporters | <0.0001 | <0.0001 | Environmental information processing | Two ZHENGs in common | Pentose phosphate pathway | <0.0001 | <0.0001 | Carbohydrate metabolism | Two ZHENGs in common | Aminoacyl-tRNA biosynthesis | 0.003 | 0.006 | Carbohydrate metabolism | Two ZHENGs in common | Galactose metabolism | 0.012 | 0.009 | Carbohydrate metabolism | Two ZHENGs in common | Starch and sucrose metabolism | 0.018 | 0.015 | Carbohydrate metabolism | Two ZHENGs in common | Pentose and glucuronate interconversions | 0.020 | 0.029 | Genetic information processing | Two ZHENGs in common | Ascorbate and aldarate metabolism | <0.0001 | >0.05 | Carbohydrate metabolism | Specific for EZ | Glycine, serine, and threonine metabolism | 0.017 | >0.05 | Amino acid metabolism | Specific for EZ | Alanine, aspartate, and glutamate metabolism | >0.05 | 0.003 | Amino acid metabolism | Specific for DZ | Amino sugar and nucleotide sugar metabolism | >0.05 | 0.003 | Carbohydrate metabolism | Specific for DZ | Glycolysis/gluconeogenesis | >0.05 | 0.005 | Carbohydrate metabolism | Specific for DZ | Purine metabolism | >0.05 | 0.042 | Nucleotide metabolism | Specific for DZ |
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-val: the statistical significance of each pathway obtained from analysis of MBRole. Class: categorization of each pathway obtained from KEGG.
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