Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies

Table 4

Effects of ethyl acetate fraction extract of Cocos nucifera (West African Tall variety) husk fibre extract on plasma urea and creatinine concentrations in mouse.

Groups (dose in mg/kg b.w.)	Urea (mmol/L)	Creatinine (mmol/L)
5% DMSO (control)	7.63 ± 0.73^a	75.62 ± 5.67^a
31.25	6.32 ± 0.50^a	88.70 ± 4.29^a
62.5	6.16 ± 1.15^a	83.98 ± 1.52^a
125	6.39 ± 0.15^a	87.62 ± 1.29^a
250	6.16 ± 0.39^a	115.77 ± 6.52^b
500	7.28 ± 0.90^a	115.03 ± 2.92^b

Values are expressed as mean ± SEM (𝑛=5). Values in the same column with different superscripts are significantly different (𝑃 < 0.05).