Research Article

Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies

Table 8

Effects of ethyl acetate fraction of Cocos nucifera (West African Tall variety) husk fibre extract on mouse plasma alkaline phosphatase, aspartate, and alanine aminotransferases activities.

Groups (dose in mg/kg b.w.)ALP (μmol/mg prot./min) ALT (mmol pyr/min/mg prot.) AST (×10−5 mmol pyr/min/mg prot.)

5% DMSO (control) 2.49 ± 0.36a81.20 ± 17.05a20.57 ± 0.30e
31.25 3.25 ± 0.18a159.39 ± 50.31a4.47 ± 0.48b
62.5 2.74 ± 0.22a122.83 ± 35.09a7.50 ± 1.00c
125 2.79 ± 0.17a222.50 ± 35.32a7.93 ± 0.24c
250 2.75 ± 0.20a 151.83 ± 22.59a0.60 ± 0.01a
5002.77 ± 0.39a 154.74 ± 11.76a15.00 ± 1.00d

Values are mean ± SEM of 5 replicates. Values with different letter superscripts from the control are significantly different ( < 0.05).