Research Article

Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies

Table 9

Effects of ethyl acetate fraction of Cocos nucifera (West African Tall variety) husk fibre extract on activities of mouse plasma lactate and glutamate dehydrogenases.

Groups (dose in mg/kg b.w.)Lactate dehydrogenase (μM/mg protein/min) Glutamate dehydrogenase (U/mg protein)

5% DMSO (control) 0.11 ± 0.01a0.08 ± 0.01a
31.250.13 ± 0.01a0.09 ± 0.02a
62.5 0.12 ± 0.01a0.36 ± 0.07b
125 0.14 ± 0.01a0.04 ± 0.010a
250 0.19 ± 0.03b0.25 ± 0.06b
500 0.13 ± 0.01a 0.07 ± 0.01a

Values are mean ± SEM of 5 replicates. Values with different letter superscripts from the control are significantly different ( < 0.05).