Ginseng Extracts Restore High-Glucose Induced Vascular Dysfunctions by Altering Triglyceride Metabolism and Downregulation of Atherosclerosis-Related Genes
Figure 2
Ginseng extracts restore acetylcholine-induced endothelium dependent vasorelaxation. After the addition of phenylephrine, doses of acetylcholine (1 × 10−9 M to 1 × 10−5 M) were added cumulatively to check the endothelial functions. Control group showed an attenuation of acetylcholine-induced vasorelaxation (Panel (a)). The insulin injected diabetic group (Panel (b)), PPT-type (30 mg/kg/day) fed diabetic group (Panel (c)), PPT-type (10 mg/kg/day) fed diabetic group (Panel (d)), PPD-type (30 mg/kg/day) fed diabetic group (Panel (e)), and PPD-type (10 mg/kg/day) (Panel (f)) fed diabetic group showed restoration of the attenuated vasorelaxation. Results were expressed as the mean ± standard error; * for the indicated comparisons.