dTGS: Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis

<table>Network used in dTGS for deduction. Red triangle node: chemical compound; blue circle node: protein; “<svg height="7.6374998" id="M75" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 31.875 7.6374998" width="31.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,7.575)"><path d="M1537 255q-71 -62 -185 -187l-22 15l102 147h-1363v50h1363l-102 147l22 15q114 -125 185 -187z" id="x27F6"></path></g>
</svg>”: one chemical component or one protein enables the expression of the next protein, raises the expression, or enhances the activity of the next protein. “<svg height="10.225" id="M76" style="vertical-align:-0.5733pt" version="1.1" viewbox="0 0 14.0625 10.225" width="14.0625" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,9.45)"><path d="M472 -42h-58v272h-379v50h379v272h58v-594z" id="x22A3"></path></g>
</svg>”: one chemical component or one protein inhibits the expression of the next protein, lowers the expression, or weakens the activity of the next protein.</table>

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Figure 1

Figure 1: dTGS: Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis 