Trichosanthes kirilowii Ethanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis through Inhibition of STAT3 Activity in Breast Cancer Cells
Figure 1
TKE and CuD inhibits cell proliferation in MCF7, SK-BR3, and MDA-MB-231 breast cancer cells. (a) Chemical structure of CuD. ((b), (c)) Different breast cancer cells were seeded into 96-well plates and treated with different concentrations of TKE (0, 10, 30, 60, 100, 200 μg/mL) or CuD (0, 0.1, 0.5, 1, 5 μg/mL) for 24 h. Cell viability measured by MTT assay. Data was reported as the percentage change in comparison to the 0 μg/mL concentration group, which were assigned 100% viability. The error bars represent the mean ± standard deviation (SD).
