Antitumor Activities of Ethyl Acetate Extracts from Selaginella doederleinii Hieron In Vitro and In Vivo and Its Possible Mechanism

Figure 4

Apoptosis induction by SD extracts in HepG2 cells. Phosphatidylserine translocation of HepG2 cells after SD extracts treatment for 24 h. The population in the region of PI⁻/Annexin V⁻ was considered to be normal cells, the population in the region of PI⁻/Annexin V⁺ was considered to be early apoptotic cells, while that of PI⁺/Annexin V⁺ was considered to be late apoptotic cells. (a) Control; (b) 25 μg/mL; (c) 50 μg/mL; (d) 75 μg/mL; (e) 100 μg/mL; (f) 150 μg/mL.

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