Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats

Figure 2

Alterations of serum proinflammatory cytokines TNFα, IL-1β, and IL-6 levels by swertianlarin in BDL rats. (a) The changes of serum TNFα in the sham operated, BDL with swertianlarin, and BDL without swertianlarin groups for 3, 7, and 14 d. (b) The alterations of serum IL-1β in sham operated, BDL with swertianlarin, and BDL without swertianlarin groups for 3, 7, and 14 d. (c) The determination of serum IL-6 in sham operated rats and BDL rats treated with or without swertianlarin after 3, 7, and 14 d. Data were analyzed as described in Materials and Methods. versus sham group with saline; , versus BDL group with saline. per group. Saline, 1% Tween-20 saline; swertianlarin dissolved in 1% Tween-20 saline.

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