Safety of Aqueous Extract of Calea ternifolia Used in Mexican Traditional Medicine

Table 3

Inhibition of CYP3A4 by the aqueous extract of C. ternifolia and controls on human baculosomes.

Plant or control	% inhibition of CYP3A4
	1500 μg/mL	750 μg/mL	375 μg/mL
C. ternifolia	59 ± 3	88 ± 4	99 ± 5
Rifampin 10 μM (inductor)		56 ± 2
Ketoconazol 10 μM (positive inhibitor)		95 ± 5

SD: ±. The extracts have significant difference against the negative control, .