Network Pharmacology Approach to Explore the Potential Mechanisms of Jieduan-Niwan Formula Treating Acute-on-Chronic Liver Failure

Table 2

The information of top 20 pathways.

GO ID	Description	Gene number	P value	Rich factor
hsa05200	Pathways in cancer	72	2.52152E-76	0.125217391
hsa05161	Hepatitis B	39	2.54498E-50	0.220338983
ko04933	AGE-RAGE signaling pathway in diabetic complications	32	2.4597E-47	0.323232323
hsa05205	Proteoglycans in cancer	34	2.48392E-38	0.155963303
hsa04668	TNF signaling pathway	28	1.72293E-37	0.243478261
hsa05162	Measles	30	1.40858E-36	0.189873418
hsa01524	Platinum drug resistance	19	2.58784E-26	0.260273973
hsa04926	Relaxin signaling pathway	20	2.80746E-22	0.147058824
ko05144	Malaria	15	3.29022E-22	0.306122449
hsa05202	Transcriptional misregulation in cancer	21	5.13459E-20	0.102941176
ko04917	Prolactin signaling pathway	14	6.54424E-18	0.2
hsa04024	cAMP signaling pathway	20	8.3844E-18	0.088495575
hsa04919	Thyroid hormone signaling pathway	16	3.71782E-17	0.130081301
ko04012	ErbB signaling pathway	14	1.4152E-16	0.162790698
ko05134	Legionellosis	12	5.14222E-16	0.218181818
ko04152	AMPK signaling pathway	14	1.75187E-14	0.116666667
hsa04910	Insulin signaling pathway	14	6.32339E-13	0.090322581
hsa04610	Complement and coagulation cascades	11	6.37071E-12	0.123595506
ko04020	Calcium signaling pathway	13	8.49125E-11	0.071428571
hsa05330	Allograft rejection	8	3.66628E-10	0.170212766