Research Article

Antimalarial Activities of Hydromethanolic Crude Extract and Chloroform Fraction of Gardenia ternifolia Leaves in Plasmodium berghei Infected Mice

Table 2

Mean percent parasitemia and mean percent parasitemia inhibition of P. berghei-infected mice treated with hydromethanolic crude extract and chloroform fraction of Gardenia ternifolia leaves in the 4-day suppressive test.

ExtractMean percent parasitemiaMean percent parasitemia inhibition

CON 10 ml/kg43.00 ± 1.580.00
CM 100 mg/kg31.35 ± 0.57acde (3)27.09
CM 200 mg/kg23.77 ± 0.52abde (3)44.72
CM 400 mg/kg13.88 ± 0.35abce (3)67.72
CF 100 mg/kg27.86 ± 0.67acde (3)35.21
CF 200 mg/kg15.50 ± 0.41abde (3)63.95
CF 400 mg/kg9.38 ± 0.25abce (3)78.19
CQ 10 mg/kg0.00 ± 0.00abcd (3)100

Data are expressed as mean ± SEM; (n = 6, CON = control, CM, crude hydromethanolic extract, CF = chloroform fraction of Gardenia ternifolia, and CQ = chloroquine). a, compared to negative control; b, compared to 100 mg/kg; c, compared to 200 mg/kg; d, compared to 400 mg/kg; e, CQ10 mg/kg: .