Comparative Analysis of Clinical and Medication Information between Chronic Hepatitis B Patients with Damp Heat Syndrome and Spleen Deficiency Syndrome

Table 2

Comparison of clinical index difference and medication between group C and group D.

	Group C (SD to DH) n = 46	Group D (sustained SD) n = 40	Statistics
Gender (male, %)	32 (69.56%)	32 (80%)	1.224^a	0.269
Age (years)	41.64 (36.54, 51.49)	48.48 (37.64, 51.98)	−1.056	0.291
Treatment
Antiviral therapy	26 (56.52%)	28 (70%)	1.664^a	0.197
Recent antivirus	10 (21.73%)	9 (22.5%)	0.007^a	0.932
Antivirus duration (days)	116 (53.5, 515)	173 (53.5, 416)	−0.090	0.928
Hepatoprotective drugs	18 (39.13%)	19 (47.5%)	0.611^a	0.434
Immunomodulator	0 (0%)	0 (0%)	—	—
Drugs that promote bile excretion	4 (8.69%)	3 (7.5%)	0.041^a	0.579
Chinese herbal medicine	17 (36.95%)	15 (37.5%)	0.003^a	0.959
Antifibrosis proprietary Chinese medicine	1 (2.2%)	3 (7.5%)	1.369^a	0.257
Untreated	4 (8.69%)	0 (0%)	3.648^a	0.077
Liver function value
TBIL (μmol/L)	0.04 (−1.87, 3.14)	−1.6 (−6.65, 2.22)	−1.979	0.048
DBIL (μmol/L)	0 (−0.7, 1)	0 (−1.72, 1.12)	−0.792	0.428
ALT (U/L)	−11 (−34, 5.75)	−19 (−96, −6.25)	−1.875	0.061
AST (U/L)	−2 (−15.25, 9.75)	−12.5 (−69, 1)	−2.130	0.033
GGT (U/L)	−1 (−23, 3)	−8.5 (−51, 3)	−1.178	0.239
ALP (U/L)	0.5 (−11.25, 8.25)	−3 (−13, 8.75)	−0.723	0.469
ALB (g/L)	1 (−2.32, 2.82)	2.19 (0.05, 5.15)	−2.156	0.031
Pre-Alb (g/L)	0 (−112, 64.5)	19 (−116.5, 70)	−0.004	0.996
TBA (μmol/L)	−2.3 (−5.05, 0.02)	−2.75 (−15.07, −0.27)	−1.130	0.258
Hepatitis B virus
HBeAg (S/CO)	−0.075 (−155.5925, 0.775)	−3.135 (−90.502, 0.385)	0.444^a	0.505
HBV-DNA (IU/mL)	−35280 (−2775275, 643.75)	−25080.5 (−5387429.25, 0)	−0.320	0.749
Liver fibrosis value
FIB-4	0.04 (−0.21, 0.36)	−0.22 (−0.86, 0.42)	−1.697	0.09
APRI	−0.02 (−0.1826, 0.069)	−0.18 (−0.83, 0.02)	−1.939	0.052
Other biomarkers
PT (S)	−0.24 (−0.82, 0.52)	0 (−0.75, 0.67)	−0.671	0.502
AFP (ng/mL)	−1.13 (−3.50, 0.05)	−0.97 (−3.18, −0.05)	−0.089	0.929
CD4/CD8	0.06 (−0.18, 0.37)	0.07 (−0.13, 0.31)	−0.320	0.749
Lipids, blood glucose
FBG (mmol/L)	−0.09 (−0.51, 0.06)	0.24 (−0.03, 0.50)	−3.355	0.001
TC (mmol/L)	−0.27 (−0.73, 0.13)	−0.32 (−1.30, 0.2)	−0.377	0.706
TG (mmol/L)	−0.03 (−0.26, 0.13)	−0.08 (−0.57, 0.19)	−0.610	0.542
HDL-C (mmol/L)	−0.16 ± 0.33	−0.09 ± 0.51	−0.818	0.416
LDL-C (mmol/L)	−0.10 ± 0.69	−0.31 ± 1.04	1.103	0.273
Blood routine test
WBC (10^9/L)	0.14 ± 1.19	0.39 ± 1.23	−0.964	0.338
LY (10^9/L)	0.04 ± 0.40	0.07 ± 0.53	−0.306	0.76
MONO (10^9/L)	0.01 (−0.10, 0.10)	−0.02 (−0.16, 0.08)	−0.737	0.461
NEUT (10^9/L)	0.11 (−0.4, 0.71)	0.55 (−0.19, 1.23)	−1.367	0.172
PLT (10^9/L)	−4.59 ± 27.25	5.63 ± 31.57	−1.610	0.111