Network Pharmacology-Based Study on the Mechanism of Gegen Qinlian Decoction against Colorectal Cancer

Table 1

The identified top 10 upregulated and downregulated DEGs between CRC tissue samples and normal tissue samples.

Upregulated DEGs			Downregulated DEGs
Gene name	Log2FC	Adjusted value	Gene name	Log2FC	Adjusted value
MMP3	4.1101	1.41E − 03	CLCA4	−4.4741	4.45E − 03
REG1A	3.8436	5.89E − 03	MS4A12	−4.4636	4.03E − 03
FOXQ1	3.5684	1.79E − 03	AQP8	−4.3366	1.91E − 03
CXCL11	3.4122	2.12E − 03	CA4	−3.6607	2.16E − 03
MMP7	3.3618	1.56E − 03	GCG	−3.6245	9.42E − 03
REG1B	3.3276	2.67E − 02	GUCA2A	−3.4325	3.83E − 03
MMP1	3.2300	2.86E −03	CLDN8	−3.3370	1.14E − 02
TCN1	3.2266	3.83E − 03	CHP2	−3.2031	1.58E − 03
SLC6A14	2.7141	6.57E − 03	NXPE4	−3.1622	3.12E − 03
CXCL3	2.6473	5.58E − 03	MAMDC2	−3.0890	3.21E − 03

DEGs, differentially expressed genes; FC, fold change.