Connexin36 Gap Junction Blockade Is Ineffective at Reducing Seizure-Like Event Activity in Neocortical Mouse Slices

Table 1

Low-magnesium seizure-like event amplitude, frequency, and length for the three groups. Data are median (95% confidence interval).

	WT; (𝑛=12, 3 animals)	WT + mefloquine; (𝑛=12, 3 animals)	Cx36 KO; (𝑛=14, 3 animals)	P value
Amplitude (μV)	129 (99–172)	134 (98–179)	146 (108–217)	.72
Frequency (/min)	3.0 (2.6–3.6)	4.3 (3.3–6.9)	3.3 (2.3–5.8)	.06
Length (s)	1.2 (0.9–1.6)	0.9 (0.8–1.5)	0.9 (0.3–2.8)	.69

WT: wild-type.
Cx36 KO, connexin36 knockout.
P values from Kruskal-Wallis test (nonparametric ANOVA) comparing the values across all three groups.