|
Gene name | Gene product |
|
(1) FA import into cells |
CD36 | CD36 molecule (thrombospondin receptor) |
LPL | Lipoprotein lipase |
VLDLR | Very-Low-Density Lipoprotein Receptor |
(2) Xenobiotic and Cholesterol transport |
ABCA1 | ATP-binding cassette, subfamily A (ABC1), member 1 |
ABCG2 | ATP-binding cassette, subfamily G (WHITE), member 2 |
(3) Acetate and FA activation and intracellular transport |
ACBP | Acyl-CoA binding protein (diazepam binding inhibitor) |
ACSL1 | Acyl-CoA synthetase long-chain family member 1 |
ACSS1 | Acyl-CoA synthetase short-chain family member 1 |
ACSS2 | Acyl-CoA synthetase short-chain family member 2 |
FABP3 | Fatty acid-binding protein, heart |
(4) Fatty acid synthesis and desaturation |
ACACA | Acetyl-coenzyme A carboxylase alpha |
FADS1 | Fatty acid desaturase 1 (delta-5 desaturase) |
FADS2 | Fatty acid desaturase 2 (delta-6 desaturase) |
FASN | Fatty acid synthase |
SCD5 | Stearoyl-CoA desaturase (delta-9-desaturase) |
(5) Triacylglycerol synthesis |
AGPAT6 | 1-Acylglycerol-3-phosphate O-acyltransferase 6 |
DGAT1 | Diacylglycerol acyltransferase 1 |
DGAT2 | Diacylglycerol acyltransferase 2 |
GPAM | Glycerol-3-phosphate acyltransferase, mitochondrial |
LPIN1 | Lipin 1 |
(6) Sphingolipid synthesis |
ASAHL | N-Acylsphingosine amidohydrolase-like |
LASS2 | LAG1 homolog, ceramide synthase 2 |
OSBP | Oxysterol-binding protein 1 |
OSBPL10 | Oxysterol-binding protein-like 10 |
OSBPL2 | Oxysterol-binding protein-like 2 |
SGPL1 | Sphingosine-1-phosphate lyase |
SPHK2 | Sphingosine kinase 2 |
SPTLC1 | Serine palmitoyltransferase, long-chain base subunit 1 |
SPTLC2 | Serine palmitoyltransferase, long-chain base subunit 2 |
UGCG | Ceramide glucosyltransferase |
(7) Lipid droplet formation |
ADFP | Adipose differentiation related protein (adipophilin, PLIN2) |
BTN1A1 | Butyrophilin, subfamily 1, member A1 |
PLIN | Perilipin |
XDH | Xanthine dehydrogenase |
(8) Ketone body Utilization |
BDH1 | 3-Hydroxybutyrate dehydrogenase, type 1 |
OXCT1 | 3-Oxoacid CoA transferase 1 |
(9) Regulation of transcription |
INSIG1 | Insulin-induced gene 1 |
INSIG2 | Insulin-induced gene 2 |
PPARG | Peroxisome proliferator-activated receptor gamma |
PPARGC1A | PPAR gamma, coactivator 1 alpha |
PPARGC1B | PPAR gamma, coactivator 1 beta |
SCAP | SREBP cleavage activating protein |
SREBF1 | Sterol regulatory element-binding transcription factor 1 |
SREBF2 | Sterol regulatory element-binding transcription factor 2 |
THRSP | Thyroid hormone responsive SPOT14 |
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