Research Article

Prevalence of Sarcopenia and Its Effect on Postoperative Complications in Patients with Crohn’s Disease

Table 1

Demographic and clinical characteristics in CD patients with or without sarcopenia.

All patients ()Sarcopenia ()Nonsarcopenia () value

Age, years0.985
Gender<0.001
 Male74 (59.7)11 (32.4)63 (70.0)
Smoking12 (9.7)0 (0)12 (13.3)0.035
Alcohol7 (5.6)0 (0)7 (7.8)0.188
BMI<0.001
BMI categories<0.001
 Underweight59 (47.6)29 (85.3)30 (33.3)
 Normal57 (46.0)4 (11.8)53 (58.9)
 Overweight8 (6.5)1 (2.9)7 (7.8)
Skeletal muscle index (cm2/m2)<0.001
Disease duration (months)0.867
Age of onset0.492
 ≤16 (A1)9 (7.3)4 (11.8)5 (5.6)
 17-40 (A2)81 (65.3)21 (61.8)60 (66.7)
 >40 (A3)34 (27.4)9 (26.5)25 (27.8)
Disease location0.063
 Ileum (L1)71 (57.3)16 (47.1)55 (61.1)
 Colon (L2)18 (14.5)9 (26.5)9 (10.0)
 Ileocolon (L3)35 (28.2)9 (26.5)26 (28.9)
Disease behavior0.026
 Nonstricturing, nonpenetrating (B1)22 (17.7)4 (11.8)18 (20.0)
 Stricturing (B2)67 (54.0)25 (73.5)42 (46.7)
 Penetrating (B3)35 (28.2)5 (14.7)30 (33.3)
Perianal disease34 (27.4)13 (38.2)21 (23.3)0.097
HBI score0.179
Preoperative therapy0.712
 No therapy22 (17.7)8 (23.5)14 (15.6)
 Steroid20 (16.1)6 (17.6)14 (15.6)
 5ASA24 (19.4)8 (23.5)16 (17.8)
 AZA36 (29.0)8 (23.5)28 (31.1)
 MTX4 (3.2)1 (2.9)3 (3.3)
 IFX18 (14.5)3 (8.8)15 (16.7)
Hemoglobin (g/L)<0.001
White cell count (cells ×109/L)0.872
Platelet0.128
Prealbumin (g/L)0.030
Albumin (g/L)0.006

BMI: body mass index; HBI: Harvey Bradshaw Index; 5-ASA: 5-aminosalicylate; AZA: Azathioprine; MTX: Methotrexate; IFX: Infliximab. values < 0.05 were highlighted in italic.