Prevalence of Sarcopenia and Its Effect on Postoperative Complications in Patients with Crohn’s Disease

Table 4

Univariate and multivariate regression analysis for risk factors of postoperative complication.

	Univariate analysis			Multivariate analysis
Variable	OR	95% CI	value	OR	95% CI	value
Male	2.041	0.878-4.746	0.098	4.080	1.205-13.814	0.024
Smoking	2.089	0.434-10.055	0.358
Alcohol	2.458	0.285-21.191	0.413
BMI			0.049			0.147
Underweight	4.308	0.499-37.207	0.184	6.353	0.444-90.812	0.173
Normal	1.628	0.179-14.771	0.625	2.501	0.165-37.947	0.509
Overweight	1			1
Sarcopenia	2.587	1.124-5.959	0.026	3.974	1.171-13.489	0.027
Duration (months)	0.996	0.988-1.004	0.313
Age of onset			0.493
<16 years (A1)	1
16-40 years (A2)	1.677	0.496-5.665	0.405
>40 years (A3)	1.037	0.265-4.052	0.958
Disease location			0.493
Ileum (L1)	1
Colon (L2)	0.964	0.247-3.768	0.958
Ileocolon (L3)	1.617	0.636-4.109	0.312
Disease behavior			0.371
Nonstricturing, nonpenetrating (B1)	1
Stricturing (B2)	0.635	0.199-2.029	0.443
Penetrating (B3)	0.531	0.219-1.288	0.161
Perianal disease	1.742	0.678-4.475	0.249
HBI score			0.027	1.167	0.911-1.495	0.381
Remission (<5)	1
Mild active (5-8)	3.103	1.240-7.761	0.016	2.485	0.674-9.160	0.172
Sever active (>8)	4.583	1.124-18.693	0.034	2.591	0.376-17.843	0.334
Hemoglobin	0.988	0.972-1.004	0.141	1.000	0.974-1.028	0.986
White cell count	1.098	0.998-1.208	0.056	0.947	0.826-1.085	0.431
Platelet	1.001	0.998-1.004	0.552
Prealbumin (g/L)	0.992	0.986-0.998	0.009	0.994	0.982-1.007	0.362
Albumin (g/L)	0.911	0.860-0.965	0.001	1.014	0.993-1.152	0.830
Emergency surgery	5.533	1.830-16.731	0.002	4.225	0.730-24.459	0.108
Indication for surgery			0.049			0.687
Stricture	1			1
Fistula	2.323	0.649-8.321	0.195	1.383	0.251-7.625	0.710
Medically refractory disease	0.896	0.219-3.670	0.879	3.221	0.457-22.695	0.240
Perforation	3.345	1.320-8.479	0.011	1.258	0.382-4.140	0.706
Type of surgery	2.754	0.967-7.848	0.058	1.393	1.345-5.633	0.642
Colostomy	4.401	1.916-10.108	<0.001	1.965	0.665-5.805	0.222

BMI: body mass index; HBI: Harvey Bradshaw Index; 5-ASA: 5-aminosalicylate; AZA: Azathioprine; MTX: Methotrexate; IFX: Infliximab. values < 0.05 were highlighted in italic.