Alterations of Serum Bile Acid Profile in Patients with Crohn’s Disease
Table 2
Concentrations of different bile acids in the entire population.
BAs (nmol/L)
CD active ()
CD remission ()
HVs ()
Total BAs
2076.5 (563.3–4168.7)
1530.9 (1084.2–3135.0)*
2978.2 (1896.1–4266.2)
Primary BAs
1451.2 (331.1–3776.4)
1044.5 (764.6–2451.5)*
2088.8 (1249.2–2908.0)
Secondary BAs
217.0 (152.9–473.5)#**
480.1 (233.8–820.4)*
795.3 (460.3–1175.9)
Conjugated BAs
675.4 (262.5–2118.7)
936.2 (394.0–1220.7)**
1479.0 (871.4–2446.4)
Unconjugated BAs
491.9 (138.3–1969.5)
867.4 (360.9–1826.4)
1295.9 (571.1–1618.4)
Results are shown as median (interquartile range). Differences were analyzed with Mann–Whitney U test. #Comparison of CD remission patients to CD active patients. *Comparison of HVs to CD active or remission patients, **.
