Research Article
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification
Figure 8
Quercetin suppresses inflammation by regulating the AMPK/MAPK/TNF-α signaling pathway in PA-induced HepG2 cells. (a) qPCR analyses of TNF-α mRNA levels in HepG2 cells stimulated by 0.4 mM PA with DMSO or 25 μM quercetin for 24 h (). (b) Western blot analysis of p-AMPK, AMPK, p-p38, p38, p-ERK, ERK, p-JNK, and JNK levels in HepG2 cells stimulated by PA with quercetin (). (c) Gray value analysis of p-AMPK/AMPK, p-p38/p38, p-ERK/ERK, and p-JNK/JNK. Data are presented as the . and .
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